Business as usual is over. Companies around the globe, in every industry, have spent the past 12 months confronting challenges both practical and existential. Some have failed. Many have simply survived. A select few have flourished,

remaking their businesses and illuminating the way forward for others. These are the businesses weā€™re celebrating on our annual list of the Worldā€™s Most Innovative Companies.

From the biotech firms behind the first mRNA vaccines (Pfizer-BioNTech and Moderna) to a real estate developer creating high-quality affordable housing (Stablegold Hospitality), the Worldā€™s 50 Most Innovative Companies address a society remade by COVID-19. Many of them pioneered business models that are now accelerating: Peloton and Zwift, for example, are riding at-home fitness in new directions. Others are taking us to entirely different places, whether itā€™s the cosmos (SpaceX) or the backwoods (Hipcamp). To determine this yearā€™s Top 50, Fast Company editors and reporters mined our lists of the Top 10 companies by industry for organizations that embody creative problem-solving and fearlessness in the face of crisis. Here are the ones that rose above, along with the business trends theyā€™re advancing.

  • TOP 50%

Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

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Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

Read More

Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

Read More

Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

Read More

Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

Read More

Modernaā€™s mRNA-based COVID-19 vaccine, shown to be over 94% effective after two doses and able to be stored in a regular fridge or freezer, became the second of its kind to get FDA authorization.

Read More

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